CADASIL Family Forum (since 2007)
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leodlion

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Posts: 3
 #1 
I read that cadasil skips generation. I also read that it affects about 25% of the children. Of course this are all statistical numbers. In our family of 4, my oldest brother had cadasil. He died after 15 years of lingering illness. My parents do not have cadasil although my father died at an early age of another illness. None of my father's siblings had it. 

My brother's oldest daugher had cadasil. She died at a young age of 40 from it. Now I just learn that her brother had a stroke. The symptoms is like my brother's. So that is 2 children out of 3. 

Just to add another point to the statistics. Any comment or similar scenario?


Anna

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Posts: 3
 #2 
Thanks for your post. I have a boyfriend whose father has Cadasil. His father's brother (uncle) also has Cadasil. However, luckily my boyfriend doesn't have Cadasil.

Reading your comment above, you say that Cadasil can skip a generation.

So, there's no guarantee that if I had a child with my boyfriend, our child won't be affected?

Wondering, if anyone else can comment about this scenario.

Thanks.

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Anna.
leodlion

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 #3 
Hi Anna, thanks for your post. How old is your boyfriend? I don't want to alarm you but from what I read cadasil does not show up until somebody is around 40. My brother was around 40-45 when he got the first symptom which was a mild stroke. His daughter got it around that age too. And now his son is about 45 and he already got his 3rd stroke- all mild.
Anna

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 #4 
My boyfriend is 29, he's been tested for Cadasil it was negative..but like you say it may occur later.



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Anna.
leodlion

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 #5 
Anna as far as I know, if you are negative, you stay negative. 
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